000			03431nam a22001577a 4500
008			190813b xxu||||| |||| 00| 0 eng d
020			_a9783540408437
050			_aRC280.B6.P43
245			_aPediatric bone and soft tissue sarcomas. / _cedited by Alberto Pappo.
260			_aNew York : _bSpringer, _c2006.
300			_axiv, 240 p. : _bill. ; _c25 cm.
500			_aIncludes and bibliographical references and index .
505			_aContents: Epidemiology of bone and soft tissue sarcomas: Descriptive epidemiology of bone tumors -- Worldwide statistics -- North American statistics -- Mortality and survivorship -- Etiology of bone sarcomas -- Bone sarcomas: future directions -- Epidemiology of soft tissue sarcomas -- Pathologic and molecular techniques used in the diagnosis and treatment planning of sarcomas: Introduction -- Standard histopathology -- Cytogenetics -- Molecular genetic techniques -- Diagnostic imaging of pediatric bone and soft tissue sarcomas -- Local control issues in pediatric bone and soft tissue sarcomas: Introduction -- Initial evaluation of bone and soft tissue sarcomas -- Imaging techniques for evaluating the primary tumor -- Staging -- Criteria for evaluating treatment response -- Outcome criteria -- Biopsy of the primary lesion -- Imaging characteristics of specific tumors -- Post-treatment imaging concerns -- Radiofrequency ablation Local control issues in pediatric bone and soft tissue sarcomas: Significance of local control in pediatric sarcomas -- Background to local control modalities -- Ewing's sarcoma -- Rhabdomyosarcoma -- Non-rhabdomyosarcomatous soft tissue sarcomas -- Osteosarcoma -- Drug discovery in pediatric bone and soft tissue sarcomas using in vivo models: Introduction -- Pediatric tumor models -- General criteria for selecting appropriate models -- Expression profiles -- Criteria for selecting RMX xenografts for drugs evaluation -- Combination therapy -- Molecular targeted agents -- Combining signal transduction inhibitors -- Future directions -- Pediatric rhabdomyosarcom: biology and results of the North American intergroup rhadomyosarcoma trials: Epidemiology -- Pathology and biology of rhabdomyosarcoma -- Clinical presentation and evaluation of extent of disease -- Staging -- Prognostic factors -- Treatment -- Role of local therapies -- Multi-instititutional trials -- Management of specific tumor sites -- Other sites -- Acute and long term effects of therapy -- Outcome and therapy of relapse -- Non-rhabdomyosarcoma soft tissue sarcomas: Epidemiology/ pathogenesis -- Pathology/ molecular pathology -- Histologic classification -- Clinical presentation and diagnosis -- Prognosis factors and clinical staging -- Treatment -- Current problems and future challenges -- Fibrous and fibrohistiocytic tumors: Fibrous and fibrohistiocytic tumors -- Soft tissue fibrous tumors -- Fibroshistiocytic tumors -- So-called fibrohistiocytic tumors -- Current problems and future challenges -- Ewing sarcoma family of tumors: Introduction -- Epidemiology -- Pathogenesis -- Pathology -- Treatment -- Future development -- Osteosarcoma: Incidence -- Etiology/ Pathogenesis -- Molecular biology -- Pathology -- Clinical presentation and natural history -- Diagnostic evaluation -- Biopsy -- Staging -- Prognostic factors -- Treatment -- Surgery -- Radiation therapy -- Recurrent disease -- Future directions.
700			_aPappo, Alberto.
942			_2lcc _cBK
999			_c6905 _d14405