000 | 01914nam a22001577a 4500 | ||
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008 | 180212b xxu||||| |||| 00| 0 eng d | ||
020 | _a0816049483 | ||
050 | _aRB155.8.P36 | ||
100 | _aPanno, Joseph. | ||
245 |
_aGene Therapy: Treating disease by repairing genes. / _cJoseph Pano. |
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260 |
_aNew York: _bFact On File, _c2005. |
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300 |
_axvii, 172p.: _bills.; _c23cm. |
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500 | _aIncludes Index. | ||
505 | _aContents: Genetic Disorders: Immune Deficiencies -- Breast Cancer -- Colon Cancer -- Melanoma -- Cystic Fibrosis -- Hemophilia -- Liver Disease -- Cardiovascular Disease -- Muscular Dystrophy -- Alzheimer's Disease -- Parkinson's Disease -- Huntington's Disease -- Viruses: The Cornerstone of Gene Therapy: Viruses are Living Crystals Viral Genomes May be RNA or DNA -- Viruses Evolved from Plasmids -- Viruses know how to Infect Cells -- The Viruses as a Gene Vehicle -- Viruses Used in Gene Therapy -- Ashi Desilva: A Promising Start -- Clinical Trials Defined -- Cells of the Immune System -- Adenosine Deaminase(ADA) -- Preliminary Research -- Clinical Procedure for ADA Gene Therapy -- Jesse Gelsinger:Down To Earth: Ornithine Transcarbamylase(OTC) -- Preliminary Research -- Clinical Procedure for OTC Gene Therapy -- The Gelsinger Clinical Trial -- The Investigation -- Conclusion Remarks -- Future Prospects: Safer Vehicles -- Reduction Immune Rejection of the Vector -- Improved Risk Assessment -- Redesigning Human Anatomy and Physiology -- Ethics of Gene Therapy -- The Belmont Report -- Clinical Trials -- Physiological Enhancement -- Cosmetic Applications -- Legal Issues: Rgulatory Agencies -- The Gelsinger Legal Trial -- International Regulation -- Resource Center -- Eukaryoke Cell Primer -- Recombinant DNA primer -- The Human Genome Project -- X- Linked Severe Combined Immunodeficiency (SCID-X1) Alzheimer,s Disease(AD) -- Huntingdon's Disease(HD). | ||
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_2lcc _cBK |
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_c6531 _d14031 |