000 01198nam a22001697a 4500
008 170608b xxu||||| |||| 00| 0 eng d
020 _a9780815342199
050 _aRC268.4.W45
100 _aWeinberg, Robert A.
245 _aThe Biology of cancer. /
_cRobert A. Weinberg.
250 _a2nd ed.
260 _aNew York:
_bGarland Science,
_c2014.
300 _axx, 876p +various pagings:
_bill.;
_c27cm.
_eCD
500 _aIncludes index.
505 _aContents: The Biology and genetics of cell and organisms -- The Nature of cancer -- Tumor viruses -- Cellular oncogenes -- Growth factors, receptors, and cancer -- Cytoplasmic signaling circuitry programs many of the traits of cancer -- Tumor suppressor genes -- pRb and control of the cell cycle clock -- p53 and apoptosis: master guardian and executioner -- External life: cell immortalization and tumorigenesis -- Muti-step tumorigenesis -- Maintenance of genomic integrity and the development of cancer -- Dialogue replaces monologue: heterotypic interactions and the biology of angiogenesis -- Moving out: invasion and metastasis -- Crowd control: tumor immunology and immunotherapy -- The Rational treatment of cancer.
942 _2lcc
_cBK
999 _c6372
_d13872