Weinberg, Robert A.

The Biology of cancer. / Robert A. Weinberg. - 2nd ed. - New York: Garland Science, 2014. - xx, 876p +various pagings: ill.; 27cm. CD

Includes index.

Contents: The Biology and genetics of cell and organisms -- The Nature of cancer -- Tumor viruses -- Cellular oncogenes -- Growth factors, receptors, and cancer -- Cytoplasmic signaling circuitry programs many of the traits of cancer -- Tumor suppressor genes -- pRb and control of the cell cycle clock -- p53 and apoptosis: master guardian and executioner -- External life: cell immortalization and tumorigenesis -- Muti-step tumorigenesis -- Maintenance of genomic integrity and the development of cancer -- Dialogue replaces monologue: heterotypic interactions and the biology of angiogenesis -- Moving out: invasion and metastasis -- Crowd control: tumor immunology and immunotherapy -- The Rational treatment of cancer.

9780815342199

RC268.4.W45