TY - BOOK AU - Miller, Leonard P. AU - Miller, Leonard P. TI - Stroke therapy: basic preclinical, and clinical directions. SN - 0471183474 AV - RC388.5.S8569 PY - 1999/// CY - New York PB - Wiley-Liss KW - Cerebrovascular disease KW - Treatment. KW - Pathophysiology. KW - Cerebrovascular Disorders KW - Therapy. N1 - Includes bibliographical references and index; Contents: Basic science: Overview: Cellular and vascular pathophisiology of stroke -- Preclinical models of stroke -- Preclinical studies: Preclinical studies of glutamate receptor antagonists for the treatment of cerebral ischemia -- Aminobutyric acid agonists for neuroprotection -- Adenosine in ischemic brain injury -- Sodium and calcium channel modulators in stroke therapy -- Intracellular events associated with cerebral ischemia -- Nitric oxide: cellular and molecular pathways in stroke -- Free radicals in stroke -- Cellular inflammation in experimental ischemic stroke -- Apoptosis:DNA damage and repair in stroke -- Reparative approaches: Growth factors and other pharmacological treatments -- Clinical direction: Clinical trials for stroke: Design considerstions -- Thrombolytic treatment of thrombotic stroke -- Perioperative stroke, encephalopathy, and CNS dysfunction -- Stroke: present and future therapy ER -